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This lack of evidence makes it difficult to draw clear conclusions regarding clinical efficacy and safety

Neuropeptide signalling proteoforms derived from VGF, somatostatin (SST) and protachykinin-1 (TAC1) showed higher abundance in AD-resilient than AD-dementia brain, whereas signalling proteoforms of cholecystokinin (CCK) and chromogranin (CHG) A/B and multiple cytoskeletal molecules were enriched in frail vs control brain

Andermann, et al (2015) Ghrelin Molecular Metabolism, 2015 Jun, Volume 4 (Issue 6), Pages 437460

Seveljevic-Jaran D, Cuzic S, Dominis-Kramaric M, et al

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8.3 Summary of meta-analyses and reviews In an extensive review focused on role of NAC in pediatric respiratory conditions Beneditti et al